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Production Description
Product Name:Houttuynia Extract
Latin Name:Houttuynia Cordata Thunb
CAS. NO.:
Plant Source:whole herb
Specification: 4:1, 10:1,20:1
Appearance: Brown Color
Test Method: TLC
Description:
In the present study, we investigated the cellular effects of herba houttuyniae extract (HHE) and the signal pathways of HHE-induced apoptosis in HL-60 human promyelocytic leukemia cell line. HHE treatment caused apoptosis of cells as evidenced by discontinuous fragmentation of DNA, the loss of mitochondrial membrane potential, release of mitochondrial cytochrome c into the cytosol, activation of procaspase-9 and caspase-3, and proteolytic cleavage of poly(ADP-ribose) polymerase. Pretreatment of Ac-DEVD-CHO, caspase-3 specific inhibitor, or cyclosporin A, a mitochondrial permeability transition inhibitor, completely abolished HHE-induced DNA fragmentation.
Function:
1. Lung abscess with purulent expectoration;
2. Heating in the lung with cough and dyspnea;
3. Acute dysentery; Acute urinary infection; Carbuncles and sores.
Applications:
Health food&beverage
Pharmaceutical
Production Description
Product Name:Houttuynia Extract
Latin Name:Houttuynia Cordata Thunb
CAS. NO.:
Plant Source:whole herb
Specification: 4:1, 10:1,20:1
Appearance: Brown Color
Test Method: TLC
Description:
In the present study, we investigated the cellular effects of herba houttuyniae extract (HHE) and the signal pathways of HHE-induced apoptosis in HL-60 human promyelocytic leukemia cell line. HHE treatment caused apoptosis of cells as evidenced by discontinuous fragmentation of DNA, the loss of mitochondrial membrane potential, release of mitochondrial cytochrome c into the cytosol, activation of procaspase-9 and caspase-3, and proteolytic cleavage of poly(ADP-ribose) polymerase. Pretreatment of Ac-DEVD-CHO, caspase-3 specific inhibitor, or cyclosporin A, a mitochondrial permeability transition inhibitor, completely abolished HHE-induced DNA fragmentation.
Function:
1. Lung abscess with purulent expectoration;
2. Heating in the lung with cough and dyspnea;
3. Acute dysentery; Acute urinary infection; Carbuncles and sores.
Applications:
Health food&beverage
Pharmaceutical
